Computer Assisted Learning (CAL) - Software Package : Experimental Pharmacology Software + Experimental Physiology Software
What is Computer Assisted Learning (CAL) - Software Package: Experimental Pharmacology Software + Experimental Physiology Software
This is the computer assisted learning (CAL) software, containing various programs which simulate animal experiments in pharmacology and physiology. The modules in the software can be used to demonstrate effect of drugs on different animals systems. The software is being used and trusted by pharmacologists and physiologists from many years. The package is user friendly, highly interactive and full of animated sequences which make simulation appear realistic.
The current version of Computer Assisted Learning (CAL) Software Package consists of the following computer simulated experiments:
Experimental Pharmacology Modules:
01-05. Experiment on effects of various drugs (Mydriatic, Miotic and Local Anaesthetic) on rabbit's eye.
01 - Epinephrine
02 - Atropine
03 - Ephedrine
04 - Physostigmine
05 - Lignocaine
06. Study of analgesic activity with the help of "Tail Flick Apparatus" (Analgesiometer).
07. Study of analgesic activity with the help of "Hot Plate Apparatus" (Analgesiometer).
08. To study analgesic activity by "Writhing Test".
09. Study of "Antihistaminic drugs/Anti allergic" drugs by mast cell stabilization method with help of "Histamine Chamber”.
10. Study of "Muscle Relaxant" activity with the help of "Rota-Rod Apparatus".
11. Study of "CNS Depressants & Stimulants" Using "Actophotometer".
12-14 . Study of drugsz acting on CNS (Including Anxiolytic Activity) using following modules
a. Elevated Plus Maze Method
b. Pole Climbing Method
- Evaluation of Anti Psychotic Drugs
- Evaluation of Sedative Drugs
15. Study of anticonvulsant activity using "Electro Convulsiometer".
16. To study PTZ induced convulsions in mice.
17. Study of effect of hepatic microsomal enzyme inducers on the phenobarbitone sleeping time in mice.
18. To study the action of strychnine/ anaesthetic on frog neurons (excitability).
19. Test for pyrogens using rabbits.
20. Effect of drugs on isolated guinea pig ileum (in-vitro).
21. To study respiratory depression effect on rabbit.
22. Study of stereotype and anti-catatonic activity of drugs on mice.
23. Experiments on thyroid and antithyroid drugs
- The effect of thyroxin, TSH and propylthiouracil on metabolism.
24. Experiments on blood sugar
- The effect of insulin (hypoglycemic activity) and alloxan on blood glucose.
25. Study of anti-inflammatory activity using carrageenan induced paw oedema method
26. Study of diuretic activity using metabolic cage
27-30. Experiments on amphibian nerve-muscle (sciatic nerve and gastrocnemius muscle) preparation.
27. Recording of Simple Muscle Twitch
28. Effect of Temperature
29. Effect of stimuli of increasing frequency.
30. Effect of stimuli of increasing strength.
31-38. Experiment on effect of various drugs on isolated frog's heart. (DRC- Dose Response Curve)
31. Epinephrine
32. Norepinephrine
33. Isoprenaline
34. Calcium chloride
35. Propranolol
36. Acetylcholine
37. Potassium chloride
38. Atropine sulphate
39-53. Experiments on effect of different drugs on dog BP & heart rate.
- Virtual Practice- Effects of drugs on the dog BP and heart rate.
39. Epinephrine (Adrenaline)
40. Norepinephrine (Noradrenaline)
41. Isoprenaline
42. Acetylcholine
43. Histamine
44. Ephedrine
45. Phentolamine
46. Propranolol
47. Atropine
48. Cimetidine
49. Carotid Occlusion
50. Central Vagus
51. Peripheral Vagus.
- Effects of vasopressor and vasodepressor with appropriate blockers.
52. Virtual Practice- Reversal action of adrenaline on blood pressure and heart rate.
53. Virtual Practice- Reversal action of acetylcholine on blood pressure and heart rate.
54-55. Experiments on "Lagendorff’s Apparatus".
- Effect of coronary vasodilators on isolated heart
- Effect of parasympathomimetics
56. Recording of DRC, evaluation of effect of agonist and antagonist and bioassay of histamine
using guinea pig ileum by matching method.
57-64. Recording of DRC & Bioassay on isolated tissues and organs by Matching, Interpolation, 3 Point & 4 Point Bioassay.
57-58. Recording of DRC and bioassay of acetylcholine using guinea pig ileum.
59-60. Recording of DRC and bioassay of oxytocin using rat uterine horn.
61-62. Recording of DRC and bioassay of serotonin using rat fundus strip.
63-64. Recording of DRC and bioassay of acetylcholine using rat ileum.
65-66. To record the DRC and to determine the pD2 value for acetylcholine on frog rectus abdominis muscle.
67-68. To record the DRC and determination of pD2 value of histamine on guinea pig ileum.
69-70. To record the DRC and determination of pD2 value of serotonin on rat stomach (fundus part) strip.
71-72. To record the DRC and determination of pA2 Value of prazosin using rat anococcygeus muscle (by Schilds plot method)
73. Study of anti-ulcer activity - using pylorus ligation method.
74. Evaluation of effect of acetylcholine (spasmogens) using rabbit jejunum.
75. Evaluation of effect of different drugs on ciliary motility.
76. Evaluation of effect of saline purgatives on frog intestine.
77-78. Determination of acute irritation of a test substance.
- Skin irritation (Including edema formation)
- Eye irritation
* In addition to above mentioned interactive experiments, modules are provided for following::
79. Animals used in experimental pharmacology.
80. Instruments used in experimental pharmacology.
81. Physiological salt solutions used in experimental pharmacology.
82. Different routes of drug administration.
83. Blood withdrawal techniques.
84. Methods of anaesthesia & euthanasia.
85. Dose calculation in pharmacological experiments..
86. Calculation of pharmacokinetic parameters.
87. Biostatistics methods in experimental pharmacology.
Experimental Physiology Modules:
01-07. AMPHIBIAN NERVE-MUSCLE EXPERIMENTS
01 Effect of temperature on simple muscle twitch.
02 Effect of two successive stimuli (of same strength) on skeletal muscle.
03 Effect of increasing strength of stimuli on skeletal muscle.
04 Effect of increasing frequency of stimuli on skeletal muscle (genesis of tetanus).
05 Effect of repeated stimuli on skeletal muscle (study of phenomenon of Fatigue).
06 Determination of conduction velocity of sciatic nerve.
07 Effect of free load (pre load) and after load on skeletal muscle.
08-13. EXPERIMENTS ON HEART (CARDIOVASCULAR SYSTEM)
08 Properties of cardiac muscles.
09 Effect of electrical stimuli application on the cardiac activity.
10 Effect of several drugs and some chemical mediators on cardiac activity.
11 The influence of the cardiac output, the peripheral resistance and vascular elasticity o
12 The measurement of the arterial tension by the Auscultatory method.
13 The influence of pressure, viscosity, radius, and length of the vessel on the flow of a liquid through the vessel.
* Additionally "Examination Mode" is provided for the experiments.
* Separate observation table/finding download option is available for each student, with student name and experiment readings/findings.
* Freely accessible additional study material in form of lab manual with the complete content of each module.
* Freely accessible additional study material on the following topics, adhering NMC guidelines.
- National Essential Drug Lists
- Standard Treatment Guidelines
- Banned Drugs List of the CDSCO
- Price Controlled Drugs List
- PvPI
- Antibiotic Guidelines.
Subscription Procedure:
1. The software can be subscribed by filling online subscription form.
2. The software can also be subscribed by sending the filled subscription formwith the requisite fees (as mentioned in form), on below mentioned address.
Address:
Director
Digital Service Division
Bureau for Helath & Education Status Upliftment
{Constitutionally Entitled As Health-Education, Bureau}
55/20, Rajat Path, Mansarovar,
Jaipur, Rajasthan,PIN-302020 (India).
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